Now showing items 22384-22403 of 41446

    Integration of vertical Single Electron Transistor into CMOS technology 

    Moral Cejudo, Alberto Jose del (Date of defense: 2021-07-14)

    Aquesta tesi presenta les investigacions realitzades cap a la integració de transistors verticals d’un sol electró (SET) en tecnologia metall-òxid-semiconductor complementari (CMOS). Dues de les principals motivacions de ...

    Integration Techniques of Fault Detection and Isolation Using Interval Observers 

    Meseguer Amela, Jordi (Date of defense: 2009-06-30)

    An interval observer has been illustrated to be a suitable approach to detect and isolate faults affecting complex dynamical industrial systems. Concerning fault detection, interval observation is an appropriate passive ...

    Integrative analysis of endocrine disruption in zebrafish (Danio rerio) 

    Martínez López, Rubén Francisco (Date of defense: 2020-09-25)

    Understanding the mode of action of different pollutants and xenobiotics in human and wildlife is a key step in environmental risk assessment. Omic technologies allow the study of the global status at different biological ...

    Integrative analysis of the functional consequences of inversions in the human genome 

    Lerga Jaso, Jon (Date of defense: 2019-11-19)

    La variación estructural contribuye de forma substancial a la diversidad genética, pero su asociación con rasgos complejos y enfermedades no se entiende del todo y merece una caracterización detallada. Esto es especialmente ...

    Integrative analysis of X-chromosome reactivation kinetics in a novel reprogramming system 

    Bauer, Moritz (Date of defense: 2020-02-14)

    The reactivation of the inactive X chromosome has the potential to provide a unique system to study the developmentally induced formation of euchromatin. However, insights into this process were hampered by the lack of ...

    Integrative approaches for gene and molecular pathway analysis in cancer 

    Solé Acha, Xavier (Date of defense: 2012-03-07)

    Al llarg de les dues darreres dècades hem tingut el privilegi d’assistir a un dels esdeveniments més importants en la història de la biomedicina: el desenvolupament del Projecte Genoma Humà. Conjuntament amb aquest fet, ...

    Integrative approaches to investigate the molecular basis of diseases and adverse drug reactions: from multivariate statistical analysis to systems biology 

    Bauer-Mehren, Anna (Date of defense: 2010-11-08)

    Despite some great success, many human diseases cannot be effectively treated, prevented or cured, yet. Moreover, prescribed drugs are often not very efficient and cause undesired side effects. Hence, there is a need to ...

    Integrative Genomic Analyses of Malignant Peripheral Nerve Sheath Tumors 

    Magallón Lorenz, Miriam (Date of defense: 2023-07-07)

    [eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with wide margins of the ...

    Integrative proteomic analysis of ovarian cancer : understanding tumour physioloy and predicting response to treatment 

    Bradbury Lobato, Melissa (Date of defense: 2020-03-20)

    High-grade serous carcinoma (HGSC) is the most common and deadly subtype of ovarian cancer. It is characterised by presenting defects in the homologous recombination repair, most frequently associated to BRCA1 mutations. ...

    Integrative study of gene expression and protein complexes 

    Toufighi, Kiana (Date of defense: 2014-10-31)

    Over the last several decades, the emerging ‘integrated’ view of the cell has triumphed over the ‘one gene/one protein/one function’ paradigm. This is illustrated by the biologically opposite effects of key regulatory ...

    Integrative study of the regulatory and epigenomic programs involved in cancer development 

    Jené i Sanz, Alba (Date of defense: 2013-04-29)

    El càncer ha estat tradicionalment considerat una malaltia fonamentalment genètica, però recentment s'està fent palès que la desregulació de mecanismes epigenètics contribueix en gran manera al desenvolupament tumoral. ...

    Integrative Systems Toxicology For Human Health 

    Sharma, Raju Prasad (Date of defense: 2018-12-03)

    Els disruptors endocrins (DE) són substàncies naturals o antropogèniques presents el ambient, aliments o productes de consum que poden alterar els equilibris hormonals en humans i animals i produir efectes adversos per a ...

    Integrative understanding of bias-motivated violence targeting underrepresented populations 

    Arias Díaz-Faes, Diego (Date of defense: 2023-11-29)

    [eng] Bias-motivated violence encompasses various types of targeted violence against underrepresented groups and is considered more potentially harmful than non-based biasmotivated violence. Research in this area has ...

    Integrative understanding of transcription in a minimal cell model 

    Lloréns Rico, Verónica (Date of defense: 2016-09-15)

    One of the major challenges of biology is to understand how entire cells or organisms behave in homeostasis and in response to perturbations. Whole-cell modeling promotes this understanding by integrating different cellular ...

    Integro-differential equations : regularity theory and Pohozaev identities 

    Ros, Xavier (Date of defense: 2014-06-19)

    The main topic of the thesis is the study of Elliptic PDEs. It is divided into three parts: (I) integro-differential equations, (II) stable solutions to reaction-diffusion problems, and (III) weighted isoperimetric and ...

    Intelectuales críticos y la transformación social en Argentina (1955-1973), Los. Historia intelectual, discursos políticos y conceptualizaciones de la violencia en la Argentina de los años sesenta-setenta. 

    Ponza, Pablo (Date of defense: 2007-06-28)

    El tema de este trabajo es la violencia política y su contexto de producción en la Argentina de los <i>sesenta-setenta</i>, y la idea central del estudio es abordar el papel jugado por los intelectuales <i>críticos o ...

    Inteligencia artificial como herramienta de soporte para la caracterización de pólipos colorrectales en imágenes de luz blanca de alta definición 

    García-Rodríguez, Ana (Date of defense: 2022-11-08)

    [spa] INTRODUCCIÓN: El cáncer colorrectal es una de las patologías con mayor prevalencia en la población mundial. La colonoscopia sigue siendo el estándar de referencia para detectar y extirpar las lesiones precursoras, ...

    Inteligencia basada en efectos para la seguridad humana de las Naciones Unidas 

    Alemán Romero, Daniel (Date of defense: 2016-11-24)

    Subsumida en un halo que tiene tanto de romántico como de impreciso, al público general se nos ha mostrado una imagen, un concepto de la inteligencia, ligado a la violencia, a la ilegalidad y a la impunidad. La inteligencia ...

    Inteligencia colectiva en los juegos sociales en Facebook. Zynga versus EA Playfish: empresas, usuarios, contenidos e interacciones. 

    Díaz Álvarez, Lluïsa (Date of defense: 2015-12-21)

    El fenómeno de los juegos sociales en Facebook ha resultado un paradigma de cambio dentro de la industria del videojuego. En este proceso vemos involucrados diversos factores como las empresas, los contenidos, los usuarios ...

    Inteligencia competitiva para la innovación en PYMEs : identificación de factores clave 

    Gallardo Rodríguez, Javier (Date of defense: 2015-12-04)

    The study focuses on SMEs in the industrial sector in Catalonia, with the aim of identifying competitive intelligence systems suitable for SMEs, the areas with the greatest potential impact with the implementation of a ...