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Now showing items 27487-27506 of 41723
Mechanics and Cellular Mechanisms Driving Zebrafish Epiboly = Mecánica y mecanismos celulares responsables de la epibolia del pez cebra
Epithelial layers constitute the skeleton of early embryos and most tissues and organs and their remodelling during development is essential for reshaping the embryo and for tissue architecture. Epithelial expansion in ...
Mechanics of boundary formation in epithelial monolayers by Eph-ephrin interactions
For an organism to develop and maintain homeostasis, cell types with distinct functions must often be separated by physical boundaries. The formation and maintenance of such boundaries is commonly attributed to local ...
Mechanics of epithelial tissue subjected to controlled pressure
(English) Epithelial sheets form specialized 3D structures suited to their physiological roles, such as branched alveoli in the lungs, tubes in the kidney, and villi in the intestine. To generate and maintain these structures, ...
Mechanism and dynamics of transgenerational epigenetic memory in Caenorhabditis elegans
Desde Darwin y Lamarck, a los biólogos les ha intrigado la posibilidad de que rasgos adquiridos debido al ambiente pudieran ser heredados. Se han descrito muchos ejemplos de este tipo debidos a perturbaciones del ambiente ...
Mechanism and stochastic dynamics of transport in Darcy-scale heterogeneous porous media
Solute transport in heterogeneous porous media in general exhibits anomalous behaviors, in the sense that it is characterized by features that cannot be explained in terms of traditional models based on the advection-dispersion ...
Mechanism of action of cyclic antimicrobial peptides
This PhD thesis is the result of the combination of experimental and computational techniques with the aim of understanding the mechanism of action of de novo cyclic decapeptides with high antimicrobial activity. By ...
Mechanism of RanGTP dependent microtubule assembly during mitosis
During mitosis, spindle assembly involves different sources of microtubules including centrosomes and chromosomes. While the role of centrosomes has been extensively studied, we still do not fully understand how chromosomes ...
Mechanism of regulation of the RPL30 pre-mRNA splicing in yeast
The mechanisms of pre-mRNA splicing regulation are poorly understood. Here we dissect how the Saccharomyces cerevisiae ribosomal L30 protein blocks splicing of its pre-mRNA upon binding a kink-turn structure including the ...
Mechanismic explanation in ecology
La ecología es una ciencia importante, tanto desde el punto de vista práctico como desde el teórico, que recientemente a comenzado a atraer la atención de los filósofos profesionales. Con todo, la investigación sobre los ...
Mechanisms and functions of the nucleus as a mechano-controller of cell contractility and migration plasticity
Living tissues are crowded and dynamic environments, in which signalling molecules and physical forces constantly act on single cells. To ensure correct tissue development and homeostasis, cells function like small processors: ...
Mechanisms and modulation of cortical rhythms and complexity
Throughout various brain states, billions of neurons interact resulting in a variety of cortical rhythms accompanied by switches between behavioral states (Gervasoni et al., 2004). As a result of the specific (1) ...
Mechanisms and pathways involved in lung tumor development in patients with chronic respiratory conditions
Chronic respiratory diseases, especially chronic obstructive pulmonary disease (COPD), and several molecular mechanisms may predispose to lung cancer (LC) development. Hypothesis: We hypothesized that different biological ...
Mechanisms behind the oncogene-induced senescence (OIS) – oncogene-induced apoptosis (OIA) decision in cells expressing p95HER2
In response to oncogenic stresses cells activate two different tumor suppressor mechanisms: Oncogene-induced senescence (OIS), a terminal cell proliferation arrest, or oncogene-induced apoptosis (OIA), which leads to cell ...
Mechanisms controlling the selective iron and zinc biofortification of rice
L’arròs es un cultiu bàsic, consumit per mes de 3 billons de persones. Es una font pobra en ferro (Fe) i zinc (Zn) per la qual cosa les poblacions pobres que depenen de l’arros per a la seva supervivència, sofreixen d’anèmia ...
Mechanisms for service-oriented resource allocation in IoT
Albeit several IoT applications have been recently deployed in several fields, including environment and industry monitoring, Smart Home, Smart Hospital and Smart Agriculture, current deployments are mostly host-oriented, ...
Mechanisms involved in motor responses of the rat small intestine in healthy conditions and after Trichinella Spiralis infection
El objetivo de este estudio es evaluar los mecanismos neurales y musculares implicados en la contracción y la relajación del músculo longitudinal del intestino delgado de rata en condiciones control y tras la infestación ...
Mechanisms involved in the remyelinating effect of sildenafil
Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system characterized by a coordinated inflammatory attack on the myelin sheaths with ensuing damage to the underlying axons. Using ...
Mechanisms of acquired resistance to anti-EGFR therapies in squamous cell carcinoma
Targeted therapies against the Epidermal Growth Factor Receptor (EGFR) are useful to treat many human cancers such as non-small cell lung cancer, colorectal cancer and head and neck cancer. However, the efficacy of such ...
Mechanisms of cytokine release induced by electronegative LDL in monocytes. The role of ceramide and the receptors CD14-TLR4
L’LDL electronegativa (LDL(-)) és una LDL modificada present en circulació amb propietats inflamatòries incloent la inducció de l’alliberament de citoquines en cèl·lules relacionades amb l’arteriosclerosi, tals com monòcits ...
Mechanisms of epigenetic regulation relevant to innate responses against pathogens
This doctoral thesis describes the participation of epigenetic mechanisms, and more specifically DNA methylation, in innate immune responses against pathogens. Innate immunity is the first barrier of defense against ...
