Biomedical applications of PolyPurine Reverse Hoogsteen hairpins: immunotherapy and gene repair 

    Jiménez Félix, Alejandro (Date of defense: 2021-01-11)

    This thesis is centered on the study of PolyPurine Reverse Hoogsteen (PPRH) hairpins technology as a tool for both gene silencing and gene editing. PolyPurine Reverse Hoogsteen (PPRH) hairpins are nonmodified single-stranded ...