Universitat de Barcelona
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Peptides are defined as compounds that contain between two and fifty amino acids connected together by amide bonds. Inside our body, peptides are natural biological messengers that play critical roles in human physiology ...
The thesis consists of two main projects: a) the development of a novel strategy to gain genetic control with spatiotemporal precision, and b) the optimisation of inhibitors of the protein kinase p38α, which has a major ...
Malaria is a parasitic disease caused by Plasmodium parasites and it is transmitted by female Anopheles mosquito. P. falciparum has a complex life cycle that includes important stages in two different hosts: a mosquito and ...
Nowadays, Nanotechnology is having an impact on practically every aspect of human life. It is a transformative technology that has influenced and will continue on electronics, computers, medicine, catalysis, energy, and ...
The concept of nanotechnology is attributed to Nobel prize winner Richard Feynman who gave a very famous, visionary in 1959 (published in 1960) during one of his lectures, saying: "the principles of physic, as far as I can ...
The goal of the present investigation is to examine the processing-structure-property relationships of multilayer graphene nanowall materials. Various plasma enhanced chemical vapor deposition (PECVD) processing parameters ...
[eng] Nanostructured semiconductors have gained significant importance due to their size- and morphology-tunable physical properties, and their ability to play a critical role in various fields such as energy conversion ...
The present Thesis is divided in three chapters: 1. Design and synthesis of new soluble epoxide hydrolase inhibitors (sEHI) The synthesis of new soluble epoxide hydrolase inhibitors based on ureas as the main ...
In the present thesis Supramolecular chemistry is exploited to approach applications in the area of Nanomedicine, and it is, focused on the design and preparation of different micro and nanotools for sensing and therapy, ...
[eng] The present Thesis is entitled “Synthesis and Magnetic Studies of Quasi-Isotropic Coordination Compounds with 3d and 4f cations”. The topic of the Thesis is to prepare coordination compounds of paramagnetic metal ...
[eng] My thesis was part of a collaborative project at the interface of neuropharmacology and medicinal chemistry that aimed to better understand the neuromodulation mechanisms associated with Alzheimer’s Disease (AD). In ...
Over the past decade, sphingolipids have emerged as a new class of modulators of various cell functions. Ceramide, which is the central molecule in the biosynthesis of sphingolipids and glycosphingolipids, is involved in ...
As an essential resource for life and most human activities, water resources protection have become one of the major focuses of scientific community, especially the increasing occurrence of emerging pollutants which have ...
[eng] Visible-light photocatalysis is currently one of the hottest research areas in organic chemistry, due to the possibility that offers to form C-C and C-Het bonds in a green, non-toxic and efficient way. Although ...
Dendrimers are a class of globular highly branched macromolecules with precise architecture. They consist of a multivalent surface with functional group, a core unit where branching starts, and the interior is made of ...
Esta Tesis Doctoral se presenta como Compendio de publicaciones. Los capítulos en los que se ha dividido la presente Tesis son los siguientes: Capítulo 1 – parte A: Enantioselective, Protecting Group-Free Synthesis of ...
Sphingolipids (SLs) are components of eukaryotic cell membranes that in the last 30 years have shown not only a structural role but also be involved in signaling processes and cellular responses. Therefore, the development ...
The present thesis is based on the development and optimization of a solid-phase strategy to prepare biaryl bicyclic pentapeptides. Suzuki-Miyaura cross-coupling reactions were used to obtain the biaryl bridge. The metholodogy ...
Combustion of diesel fuel in a diesel engine is a complex process where several pollutants are emitted in the engine exhausts. To solve this problem and at the same time accomplish with the increasingly stringent regulations ...
Functionalized ion-exchange resins are polymer-based materials that can be used as catalysts, in a wide variety of chemical reactions, to achieve highly selective formation of desired products at cost-effective rates. Among ...
