Now showing items 6217-6236 of 11070

    Investigation of the phospholipid peripheral region of lactose permease in model membranes 

    Suárez Germà, Carme (Date of defense: 2013-11-07)

    The interaction between a membrane protein and its surrounding phospholipids is thought to be crucial for the correct folding and function of the protein. This thesis is focused on the investigation of the interplay between ...

    Investigation on force detection methods for optical trapping and sensing inside living cells 

    Mas Soler, Josep (Date of defense: 2017-01-09)

    Optical Tweezers (OT) are a light-based non-invasive tool that has played an important role during the last decades in the field of biophotonics, together with the advances in optical microscopy techniques. Optical trapping ...

    Investigations in animal models of anti-NMDAR encephalitis 

    García Serra, Anna (Date of defense: 2021-09-14)

    [eng] BACKGROUND: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a neuronal antibody-mediated disease that associates with prominent neuropsychiatric symptoms and predominantly affects women of childbearing ...

    Investigations into the role of translations in abstract algebraic logic 

    Moraschini, Tommaso (Date of defense: 2016-06-08)

    This memoir is divided into two parts, devoted to two topics in (ab-stract) algebraic logic. In the first part we develop a hierarchy in which propositional logics “L” are classified according to the definability conditions ...

    Invisible structures = Estructures invisibles 

    Milne, Joanne Leonie (Date of defense: 2016-01-14)

    This thesis is an investigation into the visualization of cosmological propositions associated with string theory. Research into the work of contemporary theoretical physics led to the question, how does one visualize what ...

    Involvement of Alternative Splicing Regulation in Adipose Tissue Thermogenic Induction 

    Castellá Giner, Moisés (Date of defense: 2023-09-29)

    [emg] Alternative splicing (AS) is a gene expression regulatory mechanism that enables generation of multiple mRNA isoforms from a single gene which commonly are translated into proteins. This mechanism is tightly regulated ...

    Involvement of Foxp2 in the alterations of the basal ganglia circuitry in Huntington’s Disease 

    Rodríguez Urgellés, Ened (Date of defense: 2022-01-20)

    Huntington’s Disease (HD) is an autosomal dominant inherited neurodegenerative disorder characterized by motor, psychiatric, and cognitive manifestations. The disease is caused by an unstable expansion of the CAG trinucleotide ...

    Involvement of photoinhibition and redox balance in acclimation and developmental processes of plants 

    Muñoz Roldán, Paula (Date of defense: 2020-04-24)

    Environmental constraints and developmental processes in plants can lead to light energy excess in chloroplasts by lowering the threshold at which light becomes saturating by a lack of electron acceptors in the light-processing ...

    Involvement of Polyamines in PAMP-triggered Immunity and Systemic Acquired Resistance (SAR). Extragenic Suppressors of Immune Hybrid Incompatibility 

    Liu, Changxin (Date of defense: 2020-10-29)

    The main topic of this Thesis is to investigate the contribution of polyamines to defense in Arabidopsis thaliana and the requirement of callose deposition for full expression of effector-triggered immunity in autoimmune ...

    Involvement of Polyamines in Ribosome Biogenesis and Identification of Potential Genes Associated with Spermine Resistance in Arabidopsis thaliana 

    Murillo Villuendas, Ester (Date of defense: 2023-10-20)

    [eng] Polyamines are small polycationic molecules that contain amino groups and are found in all living organisms. This study is aimed at acquiring a comprehensive understanding of the diverse roles of polyamines in plants, ...

    Involvement of the Microtubule-Regulated RhoGEF GEF-H1 in the G12 family signaling pathways 

    Garrido Antequera, Georgina (Date of defense: 2014-09-16)

    Heterotrimeric G proteins are masters regulators of cell homeostasis. They coordinate the signaling between G protein coupled receptors (GPCRs) and their intracellular effectors. Heterotrimeric G proteins are composed of ...

    Ion beam synthesis of silicon-carbon structures and related materials 

    Calvo Barrio, Lorenzo (Date of defense: 1999-07-16)

    The goal of this dissertation is the study and characterisation of high dose Carbon (C) implantation processes into Silicon (Si) and related materials for the synthesis of Silicon Carbide (SiC). The attainment of ...

    iPSCs, CRISPR/Cas9 y protocolos de diferenciación basados en factores de transcripción para generar nuevos modelos neuronales y astrocíticos del síndrome de Sanfilippo 

    Benetó Gandia, Noelia (Date of defense: 2020-07-16)

    El objetivo general de esta tesis doctoral ha sido la generación de nuevos modelos celulares para el síndrome de Sanfilippo y su utilización para ensayar una aproximación terapéutica para esta enfermedad basada en el uso ...

    IRALIKU'K: La confrontación de los comunales. Etnografía e historia de las relaciones de propiedad en Goizueta 

    Montesinos Llinares, Lidia (Date of defense: 2013-12-16)

    Esta tesis, planteada inicialmente como un estudio de comunidad, presenta un estudio de caso sobre relaciones de propiedad en Goizueta; un pueblo euskaldun (vascófono) de unos 700 habitantes situado en el noroeste de ...

    IRBC-induced p53-dependent Cell Death in c-MYC-driven tumors mediated by loss of MCL1 

    Domostegui Fernández, Ana (Date of defense: 2019-12-05)

    The oncogene MYC is altered and its expression is deregulated in up to 70% of human cancers, including B cell neoplasms. Earlier studies in a mouse model of Eμ-MYC-driven B-cell lymphomas reported that oncogenic MYC relies ...

    Irlanda y la guerra civil española. Nuevas perspectivas de estudio 

    Soler Parício, Pere (Date of defense: 2013-05-11)

    Enmarcada en el estudio de la reacción internacional y la participación extranjera en la guerra civil española, esta Tesis analiza la respuesta al conflicto que se dio en Irlanda. Tal y como ocurrió en el resto de países ...

    The Iron Regulatory Protein/Iron Responsive Element (IRP/IRE) system: functional studies of new target mRNAs and pathological implications for novel IRE mutations 

    Luscieti, Sara (Date of defense: 2016-11-22)

    Iron is an essential micronutrient required for many cellular reactions and a tight regulation of its metabolism is therefore crucial for health. Cellular iron homeostasis relies on the coordination of iron uptake, storage ...

    Irreversibility and Criticality in the Biosphere 

    Pueyo Puntí, Salvador (Date of defense: 2003-03-25)

    This work is the result of a search for general (or nearly general) regularities at ecosystem level, and an exploration of their practical relevance in our relations with the environment.<br/>I began by adding some new ...

    Irrigation with Laser-Activated sodium hypochlorite: An antimicrobial alternative in endodontics 

    Betancourt Henríquez, Pablo Andrés (Date of defense: 2019-10-21)

    Bacteria and their sub-products are the main cause of the occurrence and perpetuation of endodontic infection. However, only a few bacterial species are seen as responsible of persistent endodontic infections, among them ...

    Irrumpir lo artístico, perturbar lo pedagógico: La Investigación Artística como espacio social de producción de conocimiento 

    Calderón García, Natalia (Date of defense: 2015-06-29)

    Irrumpir lo artístico, perturbar lo pedagógico: La Investigación Artística como espacio social de producción de conocimiento es una investigación conformada por dos partes: esta tesis y dos vídeos: En colaboración y ...