Segalés Dalmau, Jessica (Date of defense: 2011-06-08)
Els mitocondris són orgànuls citoplasmàtics que tenen un paper fonamental en múltiples processos biològics com l’oxidació de substrats i la producció d’ATP, la senyalització cel•lular, l’apoptosi, el ...
Martinez Cristobal, Paula (Date of defense: 2016-12-01)
Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear ...
Sala Cano, David (Date of defense: 2013-03-08)
DOR (Diabetes and Obesity Regulated) es va identificar com un factor de risc potencial associat a la diabetis mellitus de tipus 2. Concretament, s’observà com presentava una reducció de l’expressió del ...
Sabaté Pérez, Alba (Date of defense: 2019-10-21)
Overweight and obesity have increased dramatically during recent decades becoming a major health problem for which therapeutic options are limited. Thus, there is an urgent need to develop new safe ...
Miret Casals, Laia (Date of defense: 2014-05-23)
CHAPTER 1: Respiratory Infectious Diseases (RID) are diseases affecting the air passages, the bronchi and the lungs. They range from acute infections, such as pneumonia and bronchitis, to chronic ...
Enciso Salas, Hilda Yuliana (Date of defense: 2017-09-22)
TP53INP2 es una proteína nuclear que activa la autofagia en moscas y células eucariotas. El propósito de esta tesis doctoral fue investigar si TP53INP2 modula la autofagia mitocondrial dependiente de ...
Rodríguez Nuevo, Aida (Date of defense: 2018-04-12)
Opa1 is a mitochondrial dynamics protein responsible for the fusion of the inner mitochondrial membrane, the maintenance of cristae morphology, and involved in mitochondrial DNA stability. In this study ...