Just Baringo, Xavier (Date of defense: 2013-11-25)
The present doctoral thesis has been devoted to the development of a new synthetic strategy to obtain a new member of the thiopeptide, or thiazolyl peptide, family of antibiotics. This new member, ...
Alvira Torre, Margarita (Date of defense: 2010-10-25)
Oligonucleotides are short fragments of DNA (10-100nt) which are of great interest because their applications in molecular biology, biomedicine and nanotechnology. As a result of their ability to base ...
Llàcer Nicolás, Enric (Date of defense: 2016-01-20)
En el present treball de Tesi Doctoral s’ha desenvolupat una ruta sintètica per a l’obtenció de la fluvirucina B2 o Sch 38518. Realitzant petits canvis en cadascuna de les rutes convergents que la ...
López Ibáñez, Alba (Date of defense: 2013-11-14)
Para frenar la creciente resistencia del Plasmodium, el parásito causante de la malaria, se necesitan nuevos fármacos con modos de acción diferentes a los de los fármacos actualmente existentes. Esta ...
Pellicena Zanón, Miquel (Date of defense: 2014-01-17)
En la present Tesi Doctoral en primer lloc s’ha completat un estudi previ de reaccions aldòliques d’α-hidroxi metil cetones, tant per a grups protectors benzílics com silílics. Així, al Capítol 1 s’ha ...
Doran, Seán (Date of defense: 2012-12-14)
This doctoral thesis was focused on the design and synthesis of novel chiral ligands for application in asymmetric catalysis. One of the best examples of asymmetric catalysis is the asymmetric hydrogenation ...
Donoghue, Craig (Date of defense: 2019-07-24)
The thesis consists of two main projects: a) the development of a novel strategy to gain genetic control with spatiotemporal precision, and b) the optimisation of inhibitors of the protein kinase p38α, ...
Guardiola Bagán, Salvador (Date of defense: 2017-09-15)
Protein-protein interactions (PPIs) and protein surfaces are considered challenging targets for drug discovery. In this field, conventional medicinal chemistry (i.e. small molecules) has largely failed ...
Sánchez Pérez, Daniel (Date of defense: 2015-07-14)
1. Tendència relativa a formar enamines de diferents aldehids i cetones S’ha treballat en l’estudi per RMN de 1H de diverses espècies que estan implicades en reaccions organocatalítiques. L’equilibri ...
Melgarejo Diaz, Marta (Date of defense: 2015-11-25)
El término "polímero terapéutico" fue acuñado para describir fármacos poliméricos, polímeros conjugados a proteínas, fármacos y aptámeros, micelas de co-polímeros y vectores no-virales multicomponentes ...