Universitat Pompeu Fabra
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L’objetiu d’aquesta tesi és aprofundir en el concepte de participació i compromís dels usuaris en pàgines web i analitzar com mesurar aquesta interacció. Comencem estudiant les mètriques del comportament online, les quals ...
The general objective of this thesis is to use ancient genomic data to study the European prehistory. Thanks to the latest advances in DNA sequencing technologies, the field of ancient DNA has suffered a profound transformation ...
This thesis constitutes one of the first investigations that lie at the intersection of social influence propagation, viral marketing, and social advertising. The objective of this thesis is to take the algorithmic aspects ...
In this thesis we have developed a user-friendly tool, SeqBuster, for the analysis of small RNA (sRNA) data generated by next generation sequencing strategies, with special emphasis on deep characterization of miRNA ...
This thesis focuses on the design, development and evaluation of a series of full-body interaction experiences as tools for intervention on motivation and social initiation for children with Autism. Autism Spectrum Disorders ...
La fi del franquisme i l'inici del període conegut com la transició democràtica va significar un canvi a diversos nivells en el panorama comunicatiu que, fins aquell moment, hi havia a Barcelona. El final de les limitacions ...
Esta tesis doctoral consiste en la caracterización de la ciclina meiótica Rem1, de Schizosaccharomyces pombe. En este trabajo se analizó, inicialmente, el patrón de transcripción y expresión de rem1 durante la meiosis ...
El objetivo de esta tesis doctoral es investigar el potencial evocador que tiene la fraseología en el marco de la oralidad ficcional. Para ello, se anali-zará un corpus paralelo constituido por una novela infantil del autor ...
We did functional characterisation of Drosophila melanogaster linker histone, dH1. In the mutant state for this protein, we observed structural changes in polytene chromosomes chromocenter and nucleoli of mutant larvae. ...
La metilació de les lisines de les histones està implicada en les funcions associades a la cromatina, com l’expressió gènica o la formació d’heterocromatina. És una modificació covalent afegida per metiltransferases ...
Dsk2/UBQLN is a conserved extraproteasomal ubiquitin receptor that has been widely described as a protein involved in the ubiquitin proteasome pathway. In Drosophila, this protein has been recently reported in a non-proteolitic ...
MicroRNAs (miRNAs) are major contributors to phenotypic diversity and have a demonstrated role in evolution. We performed an analysis on how miRNA nucleotide substitutions may have contributed to human divergence from their ...
The focus of this work was to functionally characterize the CD300e receptor expressed in human monocytes and myeloid dendritic cells and investigate the implications that receptor engagement has on their biology. We provide ...
Compulsive, impulsive, and addictive disorders display some behavioral commonalities associated with a dysfunction in the regulation of motivated, goal-directed behavior. Relevant to motivated behavior, there is a set of ...
Alternative splicing (AS) is a post-transcriptional mechanism for gene expression regulation affecting almost every multiexonic gene in mammals. However, the impact of AS at the proteomic level remains under debate. In ...
The splicing regulatory protein RBM10 is frequently mutated in bladder carcinomas. Analysis of RNA sequencing data of 476 bladder tumours (UROMOL) identified 469 alternative splicing (AS) events associated with RBM10 ...
El complexos SWI/SNF són remodeladors de cromatina dependents d’ATP que es troben altament conservats al llarg de l’evolució. Aquests complexos poden regular l’accessibilitat a una zona genòmica alterant l’estat de la ...
En esta investigación doctoral se estudian los fundamentos y límites de la responsabilidad jurídico-penal del jefe o superior jerárquico de organizaciones delictivas por los delitos cometidos por sus subordinados. En ...
The purpose of this research is to elucidate the philosophical foundations of the Margin of Appreciation Doctrine of the European Court of Human Rights. For this, two basic problems are distinguished: the conceptual problem ...
Una adecuada interpretación del principio de legalidad ofrece buenas razones para admitir la analogía in bonam partem en el Derecho penal aunque de un modo limitado. Incluso cuando el juez mediante ésta excluye o limita ...
