Now showing items 1470-1489 of 3213

    Iconología del Monte de Perfección. Para una teoría de la imagen en San Juan de la Cruz 

    Serra Zamora, Anna (Date of defense: 2010-12-14)

    Este trabajo pretende establecer una teoría de la imagen en San Juan de la Cruz a partir de los textos del autor y de la interpretación del dibujo del Monte de perfección o Monte Carmelo (ca.1580). Nuestro estudio parte ...

    Identidad del orden jurídico y régimen político 

    Vilajosana Rubio, Josep M. (Josep Maria) (Date of defense: 1993-12-20)

    A la primera part, l'autor tracta de demostrar que certs criteris formals d'identitat d'un ordre jurídic (com els defensats per Austin, Kelsen y Hart) no resulten satisfactoris, perquè ignoren la repercussió que sobre ...

    Identificació i compliment del dret en la societat de la informació: reflexions sobre la teoria del sistema jurídic 

    Rosell Llorens, Mariona (Date of defense: 2017-06-20)

    L’ús generalitzat de les tecnologies de la informació i comunicació (TIC) i la connectivitat ha comportant un canvi social determinant en el context actual, la Societat de la Informació. Aquest treball planteja un exercici ...

    Identification and characterization of a novel population of memory B cells in the human intestine 

    Comerma Blesa, Laura (Date of defense: 2016-07-12)

    We found that IgM+IgD- memory (ME-M) B cells formed a large reservoir of intestinal antigen-selected IgM+ lymphocytes distinct from antigen-naïve IgM+ lymphocytes. Human ME-M B cells colonized the intestine early in life, ...

    Identification and characterization of an oncogenic form of IKKα in colorectal cancer 

    Margalef González, Pol (Date of defense: 2014-02-17)

    L’IKKα nuclear regula la transcripció gènica i ha estat relacionada amb la progressió del càncer i la metàstasis, tot i que la connexió mecanística no s’entén massa bé. Hem observat que les ...

    Identification and characterization of the molecular pathways regulating the cell cycle-linked pluripotency exit 

    Alcaine Colet, Anna (Date of defense: 2019-11-04)

    The self-renewing nature of embryonic stem cells (ESCs) is a consequence of their ability to proliferate while maintaining pluripotency, by means the capacity to differentiate into all adult cell types. Despite the remarkable ...

    Identification and functional analysis of intestinal stem cell genes in homeostasis and cancer 

    Barriga de Vicente, Francisco Martín (Date of defense: 2013-11-28)

    The first chapter of this thesis describes the study of intestinal stem cells (ISCs) and their relationship to colon cancer. We describe the transcriptional landscape of intestinal epithelial populations through the use ...

    Identification de facteurs d'intégration quantitatifs et qualitatifs des néologismes à la langue spécialisée médicale: une analyse sur corpus diachronique entre 2007 et 2015 

    Schneider, Coralie (Date of defense: 2020-04-17)

    La evolución del lenguaje médico refleja los avances médicos y se caracteriza por la creación neológica destinada a nombrar nuevos descubrimientos e innovaciones. Por lo tanto, la creación neológica, la variación terminológica ...

    Identification of a new deadenylation negative feedback loop that regulates meiotic progression 

    Belloc Rocasalbas, Eulàlia (Date of defense: 2008-12-15)

    Els oòcits de vertebrats es troben aturats a la profase I de la primera meiosi (PI). Durant el procés anomenat oogènesi, els oòctits sintetitzen i emmagatzemen grans quantitats d'ARN missatgers(ARNm)que els seran necessaris ...

    Identification of altered regulatory interactions in disease 

    Bleda Latorre, Marta (Date of defense: 2015-11-27)

    Gene regulation is a complex biological process that requires the coordinated interaction of different molecules. The integrity of the underlying mechanisms ensures the correct expression of genes that maintain cell ...

    Identification of clinically relevant genetic variation in immune-mediated inflammatory diseases using genome-wide approaches 

    Aterido Ballonga, Adrià (Date of defense: 2019-02-26)

    Rheumatoid arthritis, psoriasis, psoriatic arthritis, systemic lupus erythematosus, Crohn’s disease and ulcerative colitis are six of the most prevalent immune-mediated inflammatory diseases (IMIDs) and are associated with ...

    Identification of environmental variables in Drosophila melanogaster natural populations 

    Bogaerts Márquez, María (Date of defense: 2022-01-11)

    Entender cómo las especies se adaptan al ambiente es aún una pregunta sin resolver en el campo de la Biología Evolutiva. Mientras el foco principal siempre ha estado en la base genética, los factores ambientales responsables ...

    Identification of genetic determinants of breast cancer metastasis to the bone 

    Pavlovic, Milica (Date of defense: 2014-03-11)

    El objetivo de esta tesis era identificar determinantes genéticos de cáncer de mama con metástasis óseas. Para ello se utilizó un enfoque integral que se sustenta en células humanas de cáncer de mama, modelos experimentales ...

    Identification of genetic modifiers of penetrance in human inherited disease 

    Puigdevall Costa, Pau (Date of defense: 2019-01-17)

    Understanding the molecular basis of human inherited disease is a challenging task due to the complexity of mapping the genotype to the phenotype. The study of diseases running in families has shown that the inheritance ...

    Identification of HIV-1 reactivating quinoline compounds as bromodomain inhibitors 

    Abner, Erik (Date of defense: 2016-12-21)

    Tras la infección por VIH-1, el establecimiento de un depósito de células T en reposo infectadas latentemente con VIH impide la erradicación del virus en pacientes. Para lograr la erradicación, la terapia retroviral existente ...

    Identification of neurons controlling orientation behavior in the Drosophila melanogaster larva 

    Riedl, Julia (Date of defense: 2013-07-17)

    En este estudio hemos aprovechado la simplicidad numérica del sistema nervioso de la larva de la Drosophila melanogaster para identificar las neuronas responsables que dirigen sus movimientos de acuerdo a ciertas sustancias ...

    Identification of new LOXL2 substrates : a role for lysine oxidation in embryonic stem cell differentiation 

    Iturbide Martínez de Albéniz, Ane (Date of defense: 2016-03-15)

    Protein function is often regulated and controlled by posttranslational modifications, such as oxidation. Although oxidation has been mainly considered to be uncontrolled and nonenzymatic, many enzymatic oxidations occur ...

    Identification of novel histone marks required for the transcriptional stress response 

    Martínez Cebrián, Gerard (Date of defense: 2019-12-03)

    Upon environmental stresses such as temperature fluctuations or increases in osmolarity, yeast Saccharomyces cerevisiae induces a transcriptional reprograming in order to survive and adapt to the stress. Histone ...

    Identification of the sphingolipid desaturase DEGS1 as a novel gene for a leukodystrophy in therapeutic hope 

    Pant, Devesh Chandra (Date of defense: 2018-10-05)

    In spite of recent advances in understanding the genetic bases of leukodystrophies, a large number of clinical cases remain unexplained, suggesting that many leukodystrophy-associated genes have yet to be identified. Here ...

    Identification of versions of the same musical composition by processing audio descriptions 

    Serrà Julià, Joan (Date of defense: 2011-02-23)

    This work focuses on the automatic identification of musical piece versions (alternate renditions of the same musical composition like cover songs, live recordings, remixes, etc.). In particular, we propose two core ...