Theka, Ilda (Date of defense: 2017-02-06)
Las células madre embrionarias (ESCs) derivan de la masa cellular interna de los blastocistos y son capaces de generar las tres capas germinales. Muchos factores controlan la pluripotencia incluyendo ...
Ferrando Martorell, Eva (Date of defense: 2015-11-10)
The activation of Notch1 receptor triggers differential outcomes depending on the upstream activating ligand. This way, Jag1-Notch1 activation promotes endothelial to hematopoietic transition process ...
Lecland, Nicolas (Date of defense: 2014-04-10)
During mitotic spindle assembly, γ-tubulin ring complexes (γTuRCs) nucleate microtubules at the centrosome, around mitotic chromatin and, by augmindependent recruitment, from pre-existing microtubules. ...
Duran Nebreda, Salvador (Date of defense: 2016-01-19)
En aquesta tesi hem intentat atacar preguntes relacionades amb els orígens de la vida multicel•lular i dels comportaments cooperatius a la nostra biosfera. Particularment hem fet ús de mètodes “no ...
Tellechea Recarte, Mónica (Date of defense: 2017-05-19)
Macrophages are exquisite sensors of tissue homeostasis that can rapidly switch between pro- and anti-inflammatory or regulatory modes to respond to perturbations in the microenvironment. This functional ...
Santanach Buxaderas, Alexandra (Date of defense: 2016-10-28)
Polycomb group (PcG) proteins are transcriptional repressors that control cell identity and development. In mammals, at least five different Cbx prorteins are believed to associate with the core Polycomb ...
Pérez-Posada, Alberto (Date of defense: 2019-12-16)
El origen de la multicelularidad animal tiene sus raíces en el proceso de división celular. Conocer las bases moleculares del control de la divisón celular en animales y en sus parientes unicelulares ...
Vivori, Claudia (Date of defense: 2019-02-14)
Alternative splicing (AS) is a mechanism of post-transcriptional regulation that plays an important role during development and in the maintenance of stem cell pluripotency. The dynamics of AS ...
Bárcena Menéndez, Diego (Date of defense: 2016-10-17)
Una de las preguntas sin resolver en la biologia celular, es como las células mamíferas logran generar patrones estables como organos o seres vivos, en un entorno variable. El concepto matemático del ...
Pedone, Elisa (Date of defense: 2014-12-16)
Mouse embryonic stem (ES) cells derived from the inner cell mass of the blastocyst can be maintained in culture, under pluripotent conditions, using Serum+LIF medium. However, it has been published that ...