Rodríguez Pérez, Juan Antonio (Date of defense: 2017-01-24)
Old age comes coupled with frailty and disease and, thus, the ageing of the World’s population have spurred the interest on the causes and mechanisms of senescence. Senescence has long been a mystery, ...
Shaw, Daniel (Date of defense: 2019-12-13)
Understanding what constitutes a true Minimal Cell is a key challenge in synthetic biology. In this work, we present two new tools to aid in this endeavour. i) A novel methodology for minimising the ...
Ledda, Alice (Date of defense: 2011-05-06)
Els microsat el lits s on seq u encies d'ADN formades per repeticions en t andem de motius curts. Les curtes seq u encies repetides en t andem s on ubiq ues en els genomes dels eucariotes, tant en les ...
Dall'Olio, Giovanni Marco (Date of defense: 2013-10-28)
In this thesis we developed two approaches to study positive selection and genetic adaptation in the human genome. Both approaches are based on applications of network theory. In the first approach, ...
Mandage, Rajendra (Date of defense: 2018-01-12)
The EBV has been linked to multiple human disease phenotypes and has been associated with cancers and other infections. Recently single gene analysis and genome-wide analysis studies have been exploited ...
Carnero-Montoro, Elena (Date of defense: 2013-10-25)
The genetic basis of phenotypes that have contributed to the adaptation of species and organisms to new environments is a central question in evolutionary genetics. The recent accumulation of genetic ...
Salaverria Izaguirre, Pablo G. (Date of defense: 2019-11-22)
This PhD thesis aimed to understand the impact of temperature at different levels (biology to physics) while performing live-cell imaging. A study and characterization of the role of the temperature ...