Bellora Pereyra, Nicolás (Date of defense: 2010-02-26)
Regulation of gene transcription is a complex process involving many different proteins, some of which bind in a sequence-specific manner to DNA motifs in the gene promoter. The need to maintain specific ...
Hartasánchez Frenk, Diego Andrés (Date of defense: 2016-11-22)
Les regions duplicades del genoma, com ara les duplicacions de segments (SDs), són una característica comuna dels genomes eucariotes i han estat associades a canvis fenotípics. Donada la seva rellevància ...
López Escardó, David (Date of defense: 2018-01-15)
Opisthokonta is an eukaryotic supergroup that contains Metazoa, Fungi and their unicellular relatives. Therefore, this group provides an ideal framework to study distinct unicellular-multicellular ...
Pohl, Andy (Date of defense: 2014-10-03)
Genome-wide analysis of the nucleosome positioning and histone H1 isoform content of the T47D breast cancer cell line has found a number of observations, namely that with a gentle digestion of microccocal ...
Villanueva Cañas, José Luis (Date of defense: 2015-11-20)
Although the genome sequencing revolution is still in its infancy, we must acknowledge it as the major driver of biology since the beginning of the 21st century. The availability of a large collection ...
Cerutti, Andrea (Date of defense: 2013-07-19)
Immunoglobulin (Ig) diversification is essential for the generation of protective immune responses against intruding microbes. B cells require cognate interaction with T cells to generate protective ...
Serra Vidal, Gerard (Date of defense: 2018-12-05)
Àfrica és l'origen de totes les poblacions humanes actuals, i malgrat contenir els nivells més elevats de diversitat genètica, la seva història demogràfica ha estat relativament poc estudiada, amb moltes ...
Han, Sojung (Date of defense: 2019-10-16)
Bonobos are an interesting species to study due to their unique evolutionary features such as a peaceful social nature and hypersexual behavior. The prolonged exaggerated sexual swelling in females ...
Serrano Candelas, Eva (Date of defense: 2012-12-20)
The protein phosphatase calcineurin (Cn), together with its substrates, the transcription factors NFATc, play an essential role in several physiological processes of vertebrates, such as the immune ...
Dobón Berenguer, Begoña (Date of defense: 2018-11-23)
The evolution of the genome is driven, among other factors, by the composition of the genome, the functional output of the gene products, and by environmental pressures. Among the environmental factors, ...