Hoffmann, Tobias (Date of defense: 2021-04-08)
The splicing regulatory protein RBM10 is frequently mutated in bladder carcinomas. Analysis of RNA sequencing data of 476 bladder tumours (UROMOL) identified 469 alternative splicing (AS) events ...
Pagès Pinós, Amadís (Date of defense: 2016-10-27)
El processament de les cadenes d’àcids ribonucleics (ARN) és un mecanisme mol·lecular crucial gràcies al qual els precursors delsARN missatgers es converteixen en ARN missatgers madurs. L’exemple més ...
Singh, Babita (Date of defense: 2017-05-11)
RNA processing and their alterations are determinant to understand normal and disease cell phenotypes. In particular, specific alterations in the RNA processing of genes has been linked to widely accepted ...
Sodaei, Reza (Date of defense: 2020-05-22)
How do genomes generate different tissues, behaviours, individuals or species? We try to identify parts of the human transcriptome that we found only in a tissue. Then, we focus on inter-individual ...
Vivori, Claudia (Date of defense: 2019-02-14)
Alternative splicing (AS) is a mechanism of post-transcriptional regulation that plays an important role during development and in the maintenance of stem cell pluripotency. The dynamics of AS ...
Mechaly, Alejandro S. (Date of defense: 2011-06-27)
The recently discovered decapeptide kisspeptin and its G-protein coupled receptor form a signaling system expressed ubiquitously and are implicated in a variety of still poorly characterized functions. ...
Colì, Caterina (Date of defense: 2019-11-25)
Alternative splicing (AS) is an important step in the pathway of gene expression and regulation. The splicing process is catalyzed by the Spliceosome, a complex molecular machinery that is dynamically ...
Mantica, Federica (Date of defense: 2023-05-11)
Regulated Gene Expression (rGE) and Alternative Splicing (rAS) are two of the main mechanisms contributing to tissue-phenotypic diversity within and between species. In this thesis, we aim at characterizing ...
Tejedor Vaquero, Juan Ramón (Date of defense: 2014-06-11)
Alternative splicing is an essential regulatory layer of gene expression that expands the coding potential of the genome in multicellular organisms. The spliceosome -the sophisticated machinery involved ...
Tapial Rodríguez, Javier (Date of defense: 2018-12-14)
Alternative splicing (AS) is a post-transcriptional mechanism for gene expression regulation affecting almost every multiexonic gene in mammals. However, the impact of AS at the proteomic level remains ...
575 - General genetics. General cytogenetics (9)
576 - Cellular and subcellular biology. Cytology (5)
577 - Material bases of life. Biochemistry. Molecular biology. Biophysics (4)
616.6 - Pathology of the urogenital system. Urinary and sexual (genital) complaints. Urology (2)