Millán Ariño, Lluís (Date of defense: 2013-11-25)
Seven linker histone H1 variants exist in human somatic cells with distinct prevalence among cell types and during differentiation. Despite being key chromatin structural components, it remains elusive ...
Lloret Llinares, Marta (Date of defense: 2011-05-17)
La metilació de les lisines de les histones està implicada en les funcions associades a la cromatina, com l’expressió gènica o la formació d’heterocromatina. És una modificació covalent afegida per ...
Arcas Mantas, Aida (Date of defense: 2013-04-25)
The DNA Damage response is a crucial signaling network that preserves genome integrity. This network is an ensemble of distinct but often overlapping sub-networks, where participating components exert ...
Font Mateu, Jofre (Date of defense: 2016-12-05)
El receptor de la progesterona és un regulador clau per la proliferació de les cèl·lules de càncer de mama dependents d’hormona. El mecanisme d’acció del PR ha tingut un paper important en la resolució ...
Demajo Meseguer, Santiago (Date of defense: 2014-02-21)
Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell proliferation and accumulation of undifferentiated ...
Iannone, Camilla (Date of defense: 2014-05-23)
Intron removal is a necessary step for expression of most genes in higher eukaryotes, and alternative splice selection is a highly regulated mechanism that endows a single gene with the possibility to ...
Pascual-Reguant, Laura (Date of defense: 2018-11-23)
Les làmines nuclears (A/C i B) són els majors constituents de la làmina nuclear (NL). Els estructuralment conservats dominis associats a les làmines (LADs) estan formats per regions genòmiques que ...
Posavec, Melanija (Date of defense: 2014-06-17)
MacroH2A1.1 is one of the least understood histone variants and structural components of chromatin. Generated by alternative splicing, macroH2A1.1 differs from the other macroH2A1 isoform in its ...
Corrales Berjano, Marc (Date of defense: 2018-01-19)
This thesis reports the study of chromatin composition and conformation on the expression of integrated reporters at thousands of genomic locations in the Drosophila genome. We have adapted and improved ...
Teichmann, Sophie (Date of defense: 2013-02-04)
La monoubiquitinación de la histona H2A cumple un rol esencial en la represión génica. Diversas enzimas desubiquitinantes (DUBs) han sido identificadas, que remueven específicamente la ubiquitina de ...
575 - General genetics. General cytogenetics (5)
577 - Material bases of life. Biochemistry. Molecular biology. Biophysics (5)
576 - Cellular and subcellular biology. Cytology (4)
616 - Pathology. Clinical medicine (2)
616.7 - Pathology of the organs of locomotion. Skeletal and locomotor systems (1)