Font i Sadurní, Josep (Date of defense: 2006-06-02)
Utilitzant temperatura i pressió com a agents desnaturalitzants s'ha explorat la contribució a l'estabilitat de diferents residus del principal nucli hidrofòbic de la RNasa A. Aquests resutats suggereixen ...
Blanco Aparicio, Carmen (Date of defense: 1998-07-17)
In this work we report that potato carboxypeptidase inhibitor suppresses the growth of several human and mouse pancreatic adenocarcinoma cell lines. The inhibitor also reduces the growth of solid tumors ...
Comajoan von Arend, Pau (Date of defense: 2019-12-18)
Recombinant tissue plasminogen activator (rt-PA) is currently the only FDA-approved drug for the treatment of acute ischaemic stroke. However, the application of this therapy is limited to <5-7% of ...
Coll Constans, M. Gràcia (Date of defense: 2000-03-31)
Bovine pancreatic ribonuclease A (RNase A, EC 3.1.27.5) has been extensively studied from the structural, mechanistic and functional points of view. Within the protein folding context, it ...
Díaz Roldán, Ferran (Date of defense: 2023-07-03)
Childhood obesity is one of the most important public health problems and is associated with cardiometabolic risk factors (CMR). Low-grade inflammation plays a prominent role in the development of ...