Universitat de Girona
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Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a sudden cardiac death (SCD) associated disease characterized by the presence of polymorphic or bidirectional ventricular tachycardia during emotional or ...
Minor histocompatibility antigens (mHAgs) are peptides derived from polymorphic intracellular proteins that can be recognized in an allogeneic setting by the donor T-lymphocytes leading to the appearance of graft-versus-host ...
Pocas publicaciones estudian la utilidad preventiva de los exámenes rutinarios de vigilancia de la salud de los trabajadores. Aplicando técnicas cuantitativas y cualitativas a la información proporcionada mediante ...
Multiple sclerosis is a chronic disease of the central nervous system which has an unknown aetiology and an autoimmune mechanism. Two pathogenic processes, inflammation and neurodegeneration, converge causing a progressive ...
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and implies a huge social, medical, and economical burden. Analyses of AF risk factors in certain groups of population would allow tailored ...
Triple-negative breast cancer (TNBC) represents 20% of breast cancer and patients receive only general chemotherapy. The epidermal growth factor receptor (EGFR) is commonly expressed in TNBC and it is associated with poor ...
INTRODUCTION: Bariatric surgery (CB) is the only treatment option that has proved capable of solving the DM2. In addition to the impact on weight and comorbidities, the CB has shown a great impact on adipose tissue. THEORY: ...
Background There is few epidemiological data of peripheral arterial disease (PAD) in our environment. The recommendation of screening with ankle brachial index (ABI) in asymptomatic individuals is controversial. Evidence ...
The SCN5A gene encodes the alpha subunit of the cardiac sodium channel (NaV1.5), which is responsible for the influx of sodium ions through membrane of cardiomyocytes. Different evidences suggest that an aberrant expression ...
There are concerns about the benefit-risk ratio of pharmacologic interventions for ADHD in adults, especially in patients with ADHD and substance use disorder (SUD). Four systematic reviews of randomized placebo-controlled ...
Risk of cerebral hypoperfusion during carotid endarterectomy arterial is the main limiting factor of this technique. Shunt allows partial maintenance of cerebral perfusion during clamping. We analyze the hemodynamic ...
Increased metabolic disease in children is a major public health problem.. Epigenetic marks, such as microRNAs, could be one of the mechanisms that regulate the association maternal obesity with the development of metabolic ...
Natural death defines the death primarily attributed to an illness or an internal malfunction of the body, and not directly influenced by external forces. Most causes can be identified directly with macroscopic forensic ...
Huntington disease is a neurodegenerative disorder characterized by motor, cognitive and psychiatric dysfunction. Huntington disease is caused by an expanded CAG trinucleotide repeat at the exon 1 of the IT15 gen, which ...
Arrhythmogenic cardiac diseases are the main cause of SCD among the population under 35 years of age. Despite the improvements in genetic diagnosis, the percentage of cases that remain unexplained after genetic analysis ...
The present thesis, aims to study whether the evaluation of the CT through DTI and tractography sequences in the first 12 hours from the ICH onset, is able to predict the motor and functional outcome at 3 months. The ...
We studied the relationship between the circulating levels of the innate immune system molecules (α-defensins and BPI) and the acquired immune system (IgG, IgA and IgM) with obesity and cardiometabolic risk factors in ...
Cardiovascular risk factors control is low in peripheral artery disease patients. Leukocyte count over7.8 K/mcL or neutrophil count over 4.6 K/mcL are predictors of increased risk for heart coronary disease, cerebral ...
A prospective study on 300 morbidly obese patients who underwent gastric bypass in the province of Girona with a follow-up of 5 years.More female (288/12), mean age 43.5 years, mean weight 118.7 kg, mean BMI 46.1 kg/m2. ...
Brugada syndrome (BrS) is a cardiac electrical disease with high susceptibility to sudden cardiac death. Approximately 25-30% of BrS patients are explained by pathogenic variants in coding sequences of cardiac ion channels, ...
