Ara mostrant els elements 1-10 de 88
Garcia Cabau, Carla (Data de defensa: 2022-05-31)
Intrinsically disordered (ID) proteins or regions are protein sequences that lack stable secondary and tertiary structures. ID proteins are particularly prone to undergo liquid- liquid phase separation ...
da Rocha, Pedro Filipe Simões (Data de defensa: 2022-11-25)
[eng] Treatment landscape in early-stage NSCLC is rapidly changing after approval of anti-PD-1/PD-L1 in the neoadjuvant and adjuvant settings, respectively. However, biomarkers for patient selection, ...
Balmori de la Puente, Alfonso (Data de defensa: 2020-10-23)
Phylogenetic and phylogeographic methods allow studying the evolutionary relationships between populations and species, patterns of genetic structure, and historical events that have modelled the current ...
Iacobucci, Simona (Data de defensa: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural ...
Guberović, Iva (Data de defensa: 2021-10-01)
The histone variant macroH2A is the only structural chromatin component containing a macrodomain. In vertebrates, two genes and one event of alternative splicing give rise to three macroH2A proteins ...
Bielsa i Vilardaga, Núria (Data de defensa: 2021-06-22)
1. El paper que tenen les ceramidases en diferents malalties humanes va guanyant interès. Tot i així, la recerca en aquest àmbit ha estat obstaculitzada per la manca d’inhibidors i substrats específics ...
Blanco Ameijeiras, Jose Manuel (Data de defensa: 2023-03-24)
[eng] The Central nervous system (CNS) originates from the coordinated events that result into neural specification and the morphogenic events that shape the neural tube (NT). Then, the embryonic NT ...
Vicioso Mantis, Marta (Data de defensa: 2022-09-27)
The thesis objectives resulted from previous work from Dr Martínez-Balbás lab that characterized the cooperation between TGFβ and JMJD3 to regulate transcription at enhancers, promoters, and gene ...
Matas Gironella, Júlia (Data de defensa: 2021-12-20)
Colorectal cancer (CRC) is a major health burden with large numbers of new cases worldwide and high disease-specific mortality, despite great advances made towards improving patient clinical outcomes. ...
Escudero Ferruz, Paula (Data de defensa: 2021-06-28)
This work is focused on Barrier-to-Autointegration Factor (BAF) protein. BAF is a nuclear envelope (NE) component that binds chromatin and is required for NE reassembly (NER) at mitosis exit. Previous ...