Now showing items 58-66 of 66
Casulleras Gras, Olga (Date of defense: 2018-12-14)
Els transportadors de nucleòsids pertanyen a les famílies gèniques SLC28 i SLC29 que codifiquen pels transportadors de nucleòsids concentratius (hCNTs) i transportadors de nucleòsids equilibratius (hENTs), respectivament. ...
Sabaté Pérez, Alba (Date of defense: 2019-10-21)
Overweight and obesity have increased dramatically during recent decades becoming a major health problem for which therapeutic options are limited. Thus, there is an urgent need to develop new safe pharmacological therapies. ...
Frager, Petra (Date of defense: 2022-10-28)
[eng] Decreased physical activity and increased consumption of energy-rich food are hallmark lifestyle modifications that developed and amplified over the course of only a few decades. These changes in our daily behavior ...
Cassinelli, Silvia (Date of defense: 2023-12-15)
[eng] The Kv1.3 voltage-dependent potassium channel plays a crucial role in the immune response participating in various cellular functions like proliferation, activation, and apoptosis. The aberrant expression of this ...
Angelats Canals, Edgar (Date of defense: 2018-09-14)
G-protein coupled receptors (GPCR) constitute a complex and versatile superfamily of membrane receptors with relevance in maintaining homeostasis. The thesis project has focused in members of this superfamily: the CB1 and ...
Quesada López, Tania Paloma (Date of defense: 2018-07-09)
Obesity prevalence has tripled in the last fifty years. For this reason, it is considered the pandemic of the century. It is characterized by the accumulation of metabolic abnormalities triggered by an increase in the size ...
Tarragó Celada, Josep (Date of defense: 2020-09-16)
Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better comprehension of the process ...
Styrczewska, Katarzyna (Date of defense: 2017-09-22)
Voltage-gated K channels (Kv) is large family of channels that are expressed in both excitable and non-excitable cells. In excitable cells they contribute to the control of resting membrane potential and action potentials ...
Torrent Juan, Roger (Date of defense: 2016-06-02)
Parkinson’s disease (PD) is an incurable neurodegenerative disorder, mainly characterized by a progressive loss of midbrain dopaminergic (DA) neurons, located in the substantia nigra pars compacta (SNpc), and frequently ...