Mostrando ítems 1-10 de 31
Angelats Canals, Edgar (Fecha de defensa: 2018-09-14)
G-protein coupled receptors (GPCR) constitute a complex and versatile superfamily of membrane receptors with relevance in maintaining homeostasis. The thesis project has focused in members of this ...
Capera Aragonés, Jesusa (Fecha de defensa: 2019-12-20)
Kv1.3 is a voltage-gated potassium channel mainly expressed at the plasma membrane and at the inner mitochondrial membrane of different cell types. A dual role for the channel has been suggested: Plasma ...
Styrczewska, Katarzyna (Fecha de defensa: 2017-09-22)
Voltage-gated K channels (Kv) is large family of channels that are expressed in both excitable and non-excitable cells. In excitable cells they contribute to the control of resting membrane potential ...
Royo Garrido, Romina (Fecha de defensa: 2023-03-31)
[eng] Next-generation sequencing (NGS) has revolutionized biomedical sciences, especially in the area of cancer. It has nourished genomic research with extensive collections of sequenced genomes that ...
Irazoqui Guimon, Andrea (Fecha de defensa: 2021-12-03)
Some forms of mitochondrial dysfunction induce sterile inflammation through mitochondrial DNA (mtDNA) recognition by intracellular DNA sensors. However, our understanding of the processes operating this ...
Contreras Mostazo, Miriam Guadalupe (Fecha de defensa: 2020-10-21)
Cancer cells, including leukemic cells, can react to therapeutic treatment by altering their metabolic phenotype (“metabolic reprogramming”) to keep their accelerated proliferative state, eventually ...
Tarragó Celada, Josep (Fecha de defensa: 2020-09-16)
Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better ...
Díaz Sáez, Francisco (Fecha de defensa: 2021-02-12)
Neuregulin-4 has emerged as a novel adipokine in recent years. Several authors have previously explored the endocrine role of this adipocyte-secreted growth factor in the liver metabolism. In those ...
Casadó Anguera, Verònica (Fecha de defensa: 2018-06-14)
Catecholamines, including dopamine (DA) and norepinephrine (NE), are widely distributed in the body and constitute a class of conventional neurotransmitters and hormones that occupy key positions in the ...
Serrano Albarrás, Antonio (Fecha de defensa: 2018-11-23)
Ion channels are transmembrane proteins containing aqueous pores which, once open, permit the pass of ions through the plasma membrane. This ion flux takes places following the electrochemical gradient ...