Ara mostrant els elements 1-5 de 5
Diaz Garrido, Natalia (Data de defensa: 2021-11-17)
The gut microbiota establishes dynamic and complex interactions with the intestinal epithelium and the immune system. In this regard, commensal microbiota plays essential role in the development and ...
Jiménez Félix, Alejandro (Data de defensa: 2021-01-11)
This thesis is centered on the study of PolyPurine Reverse Hoogsteen (PPRH) hairpins technology as a tool for both gene silencing and gene editing. PolyPurine Reverse Hoogsteen (PPRH) hairpins are ...
Bayod Giron, Carles (Data de defensa: 2021-05-07)
The nuclear receptors (NR) modulate gene transcription in a ligand-dependent manner throughout different mechanisms. A set of NR, including PPARγ and LXR, are important regulators of carbohydrate and ...
Aubets Gil, Eva (Data de defensa: 2021-09-19)
This work is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as a gene silencing tool, and on the search of alternative methods for their delivery, including viral and non-viral ...
Morcillo Sánchez, Melisa (Data de defensa: 2021-03-24)
Obesity is the most common metabolic disorder that have alarmingly increased all over the world in the last few decades. The hormone insulin is one of the major endocrine axis deregulated in obesity and ...