Departament de Genètica, Microbiologia i Estadística: Envíos recientes
Mostrando ítems 1-20 de 116
Modificación enzimática de la celulosa para la producción de biomateriales
[spa] La creciente preocupación por la sostenibilidad y el impacto ambiental de los derivados del petróleo ha impulsado el desarrollo de nuevos materiales basados en fuentes renovables y amigables con el medio ambiente. ...
Estudi de l’efecte dels canvis socials sobre la conducta de tres grups familiars de goril·les de plana occidental (Gorilla gorilla gorilla) captius. A la recerca d’indicadors conductuals de benestar
[cat] Un dels pilars bàsics que componen la raó de ser dels parcs zoològics actuals és la conservació ex situ d’espècies amenaçades. Aquesta comesa, comporta el compliment d’una sèrie de requisits, entre ells, el de ...
An Omics World: Colonization and Adaptive Processes of Styela plicata
[eng] In the last decades biological invasions have emerged as a global concern, as they impact local biodiversity by disrupting ecosystem functioning and ultimately affect human health, economy and wellness. In a climate ...
Role Of The Innate Immunity In The Etiopathogenesis of Primary Sjögren Syndrome: Influence Of Viral And Immunogenetic Factors Related To Cell Adhesion Molecules In Systemic Disease And Autoantibody Profile
[eng] Sjögren Syndrome is a systemic autoimmune disease that affects the exocrine glands, most notably the salivary and lacrimal glands, although it can affect other mucosal surfaces. Inflammation at these sites leads to ...
Relevant deubiquitinating enzymes in cilium formation and function in the retina: USP48
[eng] Ciliopathies encompass a broad group of heterogeneous inherited disorders associated with dysfunction of the cilium, a ubiquitous microtubule-based organelle that translates extracellular stimuli into cellular ...
Dimensionality reduction in multigroup data: applications in integrative omics
[eng] The idea of this research is to propose dimensionality reduction methods considering multi- groups in a dataset. In multivariate analysis, there are many multigroup methods, but they have different objectives than ...
Del cicle biològic a noves estratègies vacunals pel virus de l’hepatitis A
[cat] El virus de l'hepatitis A (HAV) s'allibera de cèl·lules infectades principalment embolcallat en membranes de la pròpia cèl·lula, formant partícules quasi embolcallades (eHAV). Es creu que la biogènesis d’eHAV podria ...
Study of expression levels in MECP2 related disorders using transcriptomics and proteomics: characterizing Rett syndrome and MECP2 duplication syndrome
[eng] MECP2 is a multifunctional gene involved in multiple processes such as transcription regulation, chromatin remodelling, splicing and miRNA regulation. Malfunction of MECP2 due to loss of function mutations leads to ...
Global evaluation of the fitness and virulence determinants in the phytopathogen Ralstonia solanacearum
[eng] Losses to plant pathogens pose a major threat to global agriculture and food security worldwide. In the context of globalisation and climate change, the emergence and dispersion of pathogens resistant to conventional ...
Determining the Three-dimensional Structure of Genomes and Genomic Domains Integrating Chromosome Conformation Capture Data and Microscopy Images
[eng] Microscopy and Chromosome Conformation Capture (3C) are the two main techniques for studying the three-dimensional (3D) organization of the genome. Microscopy, allowing the visualization of genomic loci in individual ...
Noves tècniques per al control i desinfecció de virus contaminants d’aigua
[cat] Arrel de la necessitat de garantir la disponibilitat d’aigua en un context d’escassetat i assegurar-ne un bon ús que no suposi un risc microbiològic per la població, aquesta Tesi Doctoral ha estat centrada en ...
Bacteriófagos y movilización de genes de resistencia a antibióticos desde una perspectiva One-Health
[spa] En las últimas décadas la resistencia a antibióticos se ha convertido en uno de los principales problemas de salud pública a nivel global, y desde la iniciativa One-Health se han propuesto afrontar este problema, ...
Evolutionary Genomics of Panarthropoda: Study of the chemosensory gene families across phyla and the radiation of the spider genus Dysdera (Araneae, Dysderidae) in the Canary Islands
[eng] During the last decade, advances in high-throughput sequencing (HTS) technologies have increased exponentially the generation of genomic data, especially of non-model species. In this thesis, we generated and used ...
Rol de la microbiota en pacientes con bronquiectasias no asociadas a la fibrosis quística
[spa] El pulmón siempre se ha considerado estéril. Sin embargo, el campo de la microbiota pulmonar se ha visto revolucionado por el avance de las técnicas moleculares. Cada individuo tiene un perfil de microbiota único, ...
Aplicación de técnicas moleculares y químicas al estudio de la dieta, migración y estructura poblacional del rorcual común de Islandia
El objetivo global de esta tesis es ampliar el conocimiento sobre la biología y ecología del rorcual común, con foco principal en la población de rorcual común de Islandia. Dadas las numerosas incógnitas que siguen existiendo ...
Análisis de las diferencias entre células progenitoras y no progenitoras en el sistema traqueal de Drosophila melanogaster
In the Drosophila larva, most of the juvenile tissues are made up of large polyploid cells fated to die during metamorphosis stage. The dorsal trunk of the tracheal system is composed mainly of these cells, apart from the ...
Diversitat bacteriana a les etapes de potabilització de les aigües de consum
En els darrers anys l’augment poblacional així com els efectes d’un escalfament global estan minvant la capacitat i la qualitat dels recursos hídrics naturals disponibles. Els reptes als que ens enfrontem donen pas al ...
Development and regeneration of Drosophila wing imaginal discs: the role of IncRNAs and the stress sensor D-GADD45
Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides that lack protein-coding potential. Although multiple examples of functional lncRNAs have been described, particularly regulating gene ...
Understanding diversification and dispersion patterns in planarians (Tricladida, Platyhelminthes): form one to hundreds of genes
Evolutionary Biology offers a set of methods and theories to elucidate the evolutionary processes that lead to the diversification of life. With the development of sequencing technologies, the access to genetic data has ...
Exploring the role of NR2E3 in photoreceptor cell fate determination
The transcription factor NR2E3 participates in photoreceptor cell fate determination as it functions as both transcriptional repressor of cone genes and activator of rod genes. Mutations in NR2E3 cause retinitis pigmentosa ...
