Rodríguez Galindo, Miguel (Date of defense: 2023-11-13)
Tumor progression is dominated by two evolutionary forces: first mutagenesis, which provides the heritable variability where, secondly, natural selection acts. The main challenge of cancer genomics is ...
Soldevila Domènech, Natàlia (Date of defense: 2023-10-05)
Les intervencions que milloren l’estil de vida (dieta, exercici físic i entrenament cognitiu) poden frenar el declivi cognitiu en persones a risc de demència. En el context d’intervencions en l’estil de ...
Cuenca Cortés, Alejandro (Date of defense: 2023-05-17)
Nuclear pore complexes (NPCs) are necessary for stem cell maintenance, cell fate determination, and the aging process. The specific contribution of NPCs to the physiology of muscle stem cells (satellite ...
Ayala García, Amaya (Date of defense: 2023-12-04)
The project focuses on cancer and its effects on work trajectories from a life course perspective, both from a qualitative and quantitative approach. Quantitative analyses were based on a retrospective ...
Puig Tintó, Marta (Date of defense: 2023-05-02)
The exocyst is an heterooctameric protein complex that tethers secretory vesicles to the plasma membrane during exocytosis. Each exocytic event is mediated by 10-15 exocysts. However, how multiple ...
Pérez Núñez, Iván (Date of defense: 2023-03-13)
Cancer stem cells (CSCs) fuels tumours and are involved in therapy resistance, yet their contribution immunotherapy resistance and immunological properties are poorly understood. Herein, we show that ...
Altadill Balsells, Mireia (Date of defense: 2023-06-30)
Human cytomegalovirus (HCMV) causes a prevalent lifelong infection in all human populations. Although the course is generally mild and the virus remains latent, HCMV can cause severe disorders in ...
Balbastre Català, Borja (Date of defense: 2022-10-27)
Dual-specificity tyrosine-regulated kinases (DYRKs) are a conserved family of protein kinases present in all eukaryotes. In mammals, the association of DYRKs with a wide variety of putative substrates ...
Grawenhoff, Julia (Date of defense: 2024-01-24)
The local translation of messenger RNAs (mRNAs) within different neuronal compartments is a prerequisite the formation of long-term memories. mRNAs are localized via active transport along microtubules, ...
Martínez Ara, Guillermo (Date of defense: 2022-09-19)
During embryonic development, cellular forces synchronize in space and time to generate functional tissue shapes. Apical constriction is a force-generating process necessary to provoke the folding of ...