Larrañaga Carricajo, Enara (Date of defense: 2021-05-25)
Intestinal cells self-organize into 3-dimensional (3D) organoids that recapitulate the in vivo structural and functional characteristics when embedded in a 3D cell-derived protein mixture (Matrigel). ...
Vila Giraut, Anna (Date of defense: 2020-12-10)
Conventional in vitro cell culture models do not possess the complexity that the native tissues offer. Because of this, the functional properties of the tissues are not properly mimicked, which causes ...
Abad i Lázaro, Aina (Date of defense: 2023-07-20)
[eng] The standard in vitro model of the small intestine in the field of drug development still consists in a monolayer of cancer-derived cells seeded on a hard substrate. Despite the huge advances ...