Escobedo Pascual, Albert (Date of defense: 2014-11-06)
Nedd4L is a HECT-type E3 ubiquitin ligase (it covalently binds ubiquitin molecules before transferring them to the final substrate). Ubiquitination is a posttranslational modification (PTM) that labels ...
Ramírez Cota, Rosa María (Date of defense: 2016-07-05)
The depletion of MZT1 in human cells causes severe mitotic spindle defects. Depleted cells lack centrosomal γ-tubulin and arrest in mitosis with a monopolar spindle configuration. Similarly, double ...
Avó Freixo, Francisco Duque Projecto (Date of defense: 2016-10-20)
The microtubule cytoskeleton plays essential roles during cell division, migration, differentiation, defining cell morphology and organizing intracellular transport. The properties of microtubules, such ...
Nieves Calatrava, Ingrid (Date of defense: 2015-11-24)
One of the ultimate goals in biomedicine is to understand the relationship between structure, function, and dynamics of biomolecules in living cells. The biophysical tools designed to gain more insight ...
Guillén Boixet, Jordina (Date of defense: 2015-12-04)
Cytoplasmic polyadenylation element binding proteins (CPEBs) are a family of RNA-binding proteins essential for the translational regulation of mRNAs in various biological contexts. CPEBs recognize CPE ...
Chakraborty, Arka (Date of defense: 2016-07-08)
Mitochondria are intracellular double-membrane bound organelles in eukaryotic cells that act as the major suppliers of adenosine triphosphate (ATP). They possess their own DNA (mtDNA) that codes for ...
Iglesias Fernández, Javier (Date of defense: 2014-09-19)
Carbohydrates play a central role in transport and storage of energy and as molecular building blocks. Additionally, glycoconjugates, specifically glycoproteins and glycolipids, are important components ...
Terré Torras, Berta (Date of defense: 2016-12-13)
The suppression of genome instability by the DNA damage response (DDR) is critical for preventing human diseases characterized by developmental defects, infertility and in some cases, elevated cancer ...
García Cruz, Roseli Marlen (Date of defense: 2013-10-03)
H-Ras es un protooncogen que codifica para dos proteínas por splicing alternativo la p19 y la p21 (1,2). La p21 presenta mayor tamaño y se localiza en la membrana en donde realiza la función de GTPasa ...
Pallara, Chiara (Date of defense: 2016-02-04)
Proteins are large biomolecules that play essential functional and structural roles within cells and that typically act through their interaction with other proteins and biomolecules, forming highly ...