Nicolini, Federica (Date of defense: 2022-12-02)
[eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. ...
Mendieta Martínez, Laura (Date of defense: 2014-06-06)
Proteases are involved in a high number of diseases, and thus, are relevant targets. For that reason our main goal was the discovery of protease inhibitors as therapeutic agents. We focused our study ...
Serra Vidal, Bernat (Date of defense: 2014-05-27)
Alzheimer’s disease (AD) is a neurodegenerative disorder which major risk factor is age. Current drugs only offer symptomatic alleviation in AD, thus a disease-modifying treatment is urgent. The amyloid-β ...
Guixer, Bernat (Date of defense: 2014-03-31)
The blood-brain barrier (888) is a biological barrier that plays a crucial role protecting the brain from neurotoxic agents and regulating the influx and efflux of molecules required for the correct ...
Nicolás Galindo, Ernesto (Date of defense: 1988-01-01)
Como se puede comprobar por la cantidad de ejemplos que se han descrito y siguen describiéndose en la literatura, la síntesis en fase sólida se ha erigido como un método extremadamente eficaz para la ...