Ara mostrant els elements 1-10 de 12
Hartasánchez Frenk, Diego Andrés (Data de defensa: 2016-11-22)
Les regions duplicades del genoma, com ara les duplicacions de segments (SDs), són una característica comuna dels genomes eucariotes i han estat associades a canvis fenotípics. Donada la seva rellevància ...
Brasó-Vives, Marina (Data de defensa: 2019-01-18)
La duplicació és el principal mecanisme de formació de nou material genètic i d'innovació funcional. Entendre com les duplicacions sorgeixen, evolucionen, co-evolucionen i engendren noves funcions és ...
Martínez Marigorta, Urko (Data de defensa: 2012-11-12)
The aetiology of common diseases is shaped by the effects of genetic and environmental factors. Big efforts have been devoted to unravel the genetic basis of disease with the hope that it will help to ...
Farré Ramon, Xavier (Data de defensa: 2022-07-01)
Ageing is a very complex phenotype that has been widely studied, but is still largely unknown. Most of the studies focus on a single species, or on performing genome wide association studies in human ...
Morcillo Suárez, Carlos (Data de defensa: 2011-12-19)
New approaches are needed to manage and analyze the enormous quantity of biological data generated by modern technologies. Existing solutions are often fragmented and uncoordinated and, thus, they require ...
Rambla, Jordi (Data de defensa: 2023-05-18)
The advance of precision medicine depends on the availability of data that is continuously being generated in universities, research centres and hospitals world-wide. That data represents 1) the diversity ...
Lorente Galdós, Maria Belén (Data de defensa: 2011-11-11)
Identification of signatures of positive selection has long been a major issue for understanding the unique features of any given species. However, only a fraction of human genes have been interrogated. ...
Marquès i Bonet, Tomàs (Data de defensa: 2007-01-15)
The main objectives of this work are:<br/>a) To test the predictions of suppressed-recombination chromosomal speciation models on two different lineages of mammals: rodents and rimates. Suppressed-recombination ...
Heredia Genestar, José María (Data de defensa: 2020-01-28)
La mutació és un procés essencial per l’evolució, tot i que també té un rol important tant en el càncer com en altres malalties. Les mutacions no s’acumulen uniformement al llarg del genoma i la seva ...
Telford, Marco (Data de defensa: 2017-12-19)
This thesis focuses on Human herpesvirus 4 and 6, two ubiquitous viruses with a long list of putative disease associations, ranging from malignancies such as lymphomas and carcinomas to multiple sclerosis. ...