Mostrando ítems 1-8 de 8
Demajo Meseguer, Santiago (Fecha de defensa: 2014-02-21)
Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell proliferation and accumulation of undifferentiated ...
González Ramírez, Mar (Fecha de defensa: 2021-03-19)
Appropriate regulation of gene expression is necessary for correct development and homeostasis of organisms. Epigenetic mechanisms represent an additional layer of information, besides the genetic ...
Rinaldi, Lorenzo (Fecha de defensa: 2016-10-17)
DNA methylation is an essential epigenetic mechanism that regulates gene expression. While DNA methylation dynamics during embryonic formation is fairly well understood, its role in adult tissues is ...
Espejo Díaz, María Isabel (Fecha de defensa: 2021-09-20)
Polycomb group (PcG) proteins are transcriptional repressors that control development and cell fate. Polycomb Repressive Complex 2 (PRC2) misfunction has been recurrently associated with embryonic ...
Jain, Payal (Fecha de defensa: 2015-06-11)
Polycomblike proteins (PCLs) have been shown to regulate Polycomb Repressive Complex 2 (PRC2) by enhancing its catalytic activity and guiding PRC2 to its target genes in embryonic stem cells. However, ...
Chammas, Paul (Fecha de defensa: 2019-11-29)
Polycomb repressive complex 2 (PRC2) is a key epigenetic regulator of gene expression. It acts through its histone-modifying activity, as it is responsible of di- and trimethylating the tail of histone ...
Uribesalgo Micàs, Iris (Fecha de defensa: 2010-11-24)
The c-Myc transcription factor is a key player in cell homeostasis, being commonly deregulated in human carcinogenesis. In this PhD thesis we have addressed the question how regulatory mechanisms ...
Morey Ramonell, Lluís (Fecha de defensa: 2008-02-01)
En mamíferos, así como en plantas, mutaciones en AND helicasas/ATPasas del la família SNF2, no solo afectan a la estructura de la cromatina, sino que también afectan al patrón global de la metilación ...
575 - Genética general. Citogenética general. Inmunogenética. Evolución. Filogenia (2)
616 - Patología. Medicina clínica. Oncología (2)
616.4 - Patología del sistema linfático, órganos hematopoyéticos, endocrinos (2)
573 - Biología general y teórica (1)