Cabrerizo Granados, David (Date of defense: 2020-11-30)
Snail1 is a transcriptional factor with a great relevance in tumor development as it is required for epithelial to mesenchymal transition and activation of cancer-associated fibroblasts (CAF). In this ...
Lambies Barjau, Guillem (Date of defense: 2019-01-10)
Cancer cells undergo epithelial-to-mesenchymal transition (EMT) to dissociate from the primary tumor and to survive to chemotherapy. EMT is controlled by Snail1, a transcriptional factor also required ...
Escrivà Izquierdo, María (Date of defense: 2008-06-20)
The product of the snail1 gene (SNAIL1) is a transcriptional repressor required for triggering the epithelial-to-mesenchymal transition (EMT). SNAIL1 transcription is induced when epithelial cells are ...
Alba Castellón, Lorena (Date of defense: 2016-02-17)
Snail transcription factor 1 triggers epithelial to mesenchymal transition. In cancer, this process provides tumoral epithelial cells with invasive characteristics. In this thesis, we demonstrated that ...
Iturbide Martínez de Albéniz, Ane (Date of defense: 2016-03-15)
Protein function is often regulated and controlled by posttranslational modifications, such as oxidation. Although oxidation has been mainly considered to be uncontrolled and nonenzymatic, many enzymatic ...
Herranz Martín, Nicolás (Date of defense: 2011-09-23)
The epithelial to mesenchymal transition (EMT) is a highly conserved cellular program that allows well-‐differentiated epithelial cells to convert to motile mesenchymal cells. ...
Gonzàlez Busqué, Núria (Date of defense: 2017-09-18)
Snail1 transcription factor is the key inducer of epithelial-to-mesenchymal transition (EMT). Here, we describe a novel role for Snail1 on the regulation of telomere integrity and transcription as well ...
Guaita Esteruelas, Sandra (Date of defense: 2005-09-21)
Durant la transició Epiteli-Mesènquima (TEM), el factor de transcripció Snail reprimeix la transcripció de l'E-cadherina unint-se a les caixes E presents en el promotor d'aquest gen.<br/>Les cèl·lules ...
Bruch Oms, Marina (Date of defense: 2022-12-12)
Tumors are complex masses composed by multiple cell types, such as cancer associated fibroblasts (CAFs) and macrophages, that interact with each other promoting the tumor progression. Snail1 is a ...