Mostrando ítems 1-10 de 45
Mariani, Francesco (Fecha de defensa: 2016-07-05)
Although sygma-aryl and sygma-vinylpalladium(II) complexes are commonly used as electrophiles in C—C bond forming reactions, recent research has demonstrated that the same palladium intermediates can ...
Ghirardi, Elena (Fecha de defensa: 2016-07-28)
The first objective of this Thesis was the study of the preparation of octhydro-1H-cyclopenta[b]pyridines and octahydro-1H-indoles, through the synthesis of (R)-phenylglycinol derived tricyclic lactams. ...
Griñán Ferré, Christian (Fecha de defensa: 2016-12-12)
Existe una correlación positiva entre el incremento de la esperanza de vida y el aumento de las enfermedades crónicas. Se ha establecido que el envejecimiento es el principal factor de riesgo en la ...
Botteri, Gaia (Fecha de defensa: 2018-03-14)
Diabetes represents one of the biggest health challenges of the 21st century. Insulin resistance is the primary defect in the most common form of diabetes, type 2 diabetes mellitus (T2D), and is defined ...
Sanllehí Figuerola, Pol (Fecha de defensa: 2016-11-02)
Sphingolipids (SLs) are essential structural and signaling molecules of eukaryotic cells. An important group of SLs metabolites are those showing a phosphate group at the C1‒ OH. Among them, ...
Saborit Villarroya, Gisela (Fecha de defensa: 2016-07-19)
En la present tesi doctoral s’ha desenvolupat una estratègia per obtenir els esquelets dels quatre alcaloides licopodi representatius a partir d’un mateix intermedi sintètic comú 1, de manera semblant ...
Sangüesa Puigventós, Gemma (Fecha de defensa: 2017-04-18)
En les últimes dècades, l’increment del consum de sucres, especialment de fructosa, s’ha associat al desenvolupament de la obesitat i d’alteracions metabòliques com ara diabetis, hipertensió i malalties ...
Ordeix i Utiel, Sergi (Fecha de defensa: 2022-11-11)
[cat] Els alcaloides indòlics monoterpènics del grup leuconolam-leuconoxina-mersicarpina [(–)- mersicarpina, (–)-leuconoxina, (+)-melodinina E] i la (–)-kopsiyunnanina K presenten una interessant activitat ...
Aguilar Recarte, David (Fecha de defensa: 2021-09-20)
Type 2 diabetes (T2D) is a multifactorial disease that comprises metabolic defects in multiple organs. Several studies have shown that the presence of a chronic low-state inflammatory process induces ...
Alea Reyes, María Elisa (Fecha de defensa: 2017-07-17)
The present thesis is included in the area of Nanomedicine and supramolecular chemistry, focused on the design and preparation of different nano and microtools for delivery, therapy and sensing. Initially, ...