Mostrando ítems 11-20 de 31
Barros, Susana Raquel Costa (Fecha de defensa: 2020-02-13)
OPA1 is a dynamin-related protein that is responsible for the fusion of the internal mitochondrial membrane and essential to control the morphology of the mitochondrial cristae. Thus, it directly impacts ...
Sabaté Pérez, Alba (Fecha de defensa: 2019-10-21)
Overweight and obesity have increased dramatically during recent decades becoming a major health problem for which therapeutic options are limited. Thus, there is an urgent need to develop new safe ...
Sastre Martinez, Daniel (Fecha de defensa: 2022-04-08)
Kv1.3 plays a crucial role in leukocytes, where it regulates activation and proliferation. In these cells, Kv1.3 is coexpressed with modulatory subunit KCNE4. This ancillary peptide acts as a dominant ...
Sánchez Soto, Marta (Fecha de defensa: 2017-01-16)
From the D2‐like receptors (D2,D3, D4), only D4 receptor (D4R) has been described as “promiscuous” since it can be activated both by dopamine (DA) and norepinephrine (NE) and function as a noradrenergic ...
Rodríguez Nuevo, Aida (Fecha de defensa: 2018-04-12)
Opa1 is a mitochondrial dynamics protein responsible for the fusion of the inner mitochondrial membrane, the maintenance of cristae morphology, and involved in mitochondrial DNA stability. In this study ...
Zodda, Erika (Fecha de defensa: 2019-12-13)
The endothelium plays a pivotal role in the development of cardiovascular disease (CVD) and emerging evidence indicates that pathological blood vessel responses and endothelial dysfunction are associated ...
Baptista, Inês do Carmo Viegas (Fecha de defensa: 2022-04-07)
Leukaemia is one of the types of cancer where treatment resistance is prevalent. Better understanding of leukemic cells metabolism opens possibilities for new therapeutic strategies and better prognosis ...
Nukala, Sarath Babu (Fecha de defensa: 2019-05-23)
The vascular endothelium is one of the major targets of oxidative stress, playing an important role in the development of vascular-related disorders, such as atherosclerotic disease1. Oxidative stress ...
Foguet Coll, Carles (Fecha de defensa: 2019-12-20)
Metabolism is a hallmark of life and underlies most biological processes in both health and disease. For instance, dysregulation of liver metabolism underlies multifactorial disorders such as diabetes ...
Serrano Novillo, Clara (Fecha de defensa: 2020-01-17)
Voltage gated K+ channels (Kv) are transmembrane proteins that allow the pass-thorugh of potassium ions, regulating the electrochemical gradient of the cell membrane. This way, they modulate several ...