Mostrando ítems 35615-35634 de 41912
Villa, Raffaella (Fecha de defensa: 2007-12-10)
Mi trabajo ha estado enfocado en la implicación de los diferentes mecanismos epigenéticos de PML-RARa en la inducción de la leucemia promielocítica aguda (APL).<br/>En particular yo estudié el rol de MBD1, un miembro de ...
Pérez Martí, Albert (Fecha de defensa: 2017-03-13)
Obesity and associated metabolic diseases have reached epidemic proportions, affecting not only high-income countries but also low- and middle-income ones. In this context, the search for therapeutic approaches to treat ...
Sierra Cruz, Marta (Fecha de defensa: 2022-04-25)
La prevalença de l'obesitat i l'envelliment s'han incrementat dràsticament en les últimes dècades. L'obesitat s'associa a una pèrdua de la funció de barrera intestinal i a canvis en la microbiota (disbiosis). Això provoca ...
Madanat, Philip Odeh (Fecha de defensa: 2016-02-01)
This field study investigates the intricate relationship between Friday sermon (khutba) and the worshippers' public opinion in Jordan. Prompted by the taboo label assigned to scholarship on khutba, it probes whether the ...
Rosario, Alexandra Carrilho do (Fecha de defensa: 2018-06-12)
This Thesis has been divided into three different chapters, the regulation of Fsp27 during the fasting adaptation, the transcriptional regulation of Fsp27 in liver and finally the role of FSP27 as a lipid-droplet protein ...
Vinaixa Forner, Judit (Fecha de defensa: 2019-03-25)
Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive tumors; mostly due to its lack of symptoms, resulting in late diagnosis, and also due to the presence of an aggressive tumor microenvironment. Importantly, ...
Hervera Abad, Arnau (Fecha de defensa: 2012-11-16)
El dolor neuropàtic es causat per una lesió o malaltia del sistema nerviós somatosensiorial, i es caracteritza per la presencia d'alodínia e hiperalgèsia. Actualment el seu tractament es basa en la teràpia amb opioids, ...
López del Hoyo, Natalia (Fecha de defensa: 2014-03-14)
In the last two decades, it has been done a thoroughly research about the role of Guanylate Cyclase Activating Proteins (GCAPs) in photoreceptor cells of the retina as activity regulators of Retinal Guanylate Cyclase ...
Aguilera Pujabet, Mònica (Fecha de defensa: 2014-11-18)
La microbiota comensal del intestino se considera un factor clave en la homeostasis gastrointestinal. Las alteraciones funcionales gastrointestinales (síndrome del intestino irritable, SII) y las enfermedades inflamatorias ...
Núñez Álvarez, Yaiza (Fecha de defensa: 2017-07-26)
HDAC11 is the newest member of the histone deacetylase (HDAC) family and one of the less studied. Its expression was described to be enriched in skeletal muscle tissues from the first moment of its discovery, yet now after ...
Martínez Garza, Úrsula Montserrat (Fecha de defensa: 2020-11-02)
The excessive consumption of calorie-rich foods, together with a sedentary lifestyle, drive the actual global obesity pandemic. Obesity is the leading cause of several other metabolic disorders, such as diabetes, cardiovascular ...
Dereli, Begüm (Fecha de defensa: 2021-11-11)
This thesis is a compilation of three articles that aim to contribute to a deeper understanding of the role of higher education in refugees’ integration by focusing on urban refugees’ experiences who settled in a neighboring ...
Román González, Lidia (Fecha de defensa: 2014-01-31)
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the previous one. To ...
Bae, Hansol (Fecha de defensa: 2024-04-26)
Epigenetic modification serves as a crucial mechanism in regulating gene expression and facilitating cellular adaptation to environmental stress. This study aimed to identify histone residues and their associated ...
Le Pannérer, Marguerite-Marie (Fecha de defensa: 2022-01-21)
The relevance of epigenetics is increasingly recognized in haematopoietic diseases such as myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML). Variants of histones, such as macroH2As, and chromatin remodellers, ...
Arroba Hidalgo, Ester (Fecha de defensa: 2021-02-10)
The human leukocyte antigen-G (HLA-G) is a non-classic MHC class I molecule. It is called “non-classic” because it differs from classic MHC class I molecules due to its very low amount of polymorphism and highly tissue-restricted ...
Robles Hellín, Claudia (Fecha de defensa: 2014-07-07)
Polyomaviruses are suspected to cause cancer in humans although to date Merkel cell polyomavirus (MCPyV) is the only proven human carcinogen. Potential associations of up to nine polyomaviruses with 468 lymphoproliferative ...
Sánchez Molina, Paula (Fecha de defensa: 2021-10-15)
L’envelliment és un procés fisiològic que afecta a tots els organismes vius. Al sistema nerviós central (SNC), aquest procés es caracteritza per neuroinflamació i deteriorament cognitiu, sent el principal factor de risc ...
Qin, Liyun (Fecha de defensa: 2022-07-14)
Introducció: Les malalties respiratòries cròniques com el càncer de pulmó (CP), la malaltia pulmonar obstructiva crònica (MPOC) i les bronquiectàsies afecten tant les estructures pulmonars com els òrgans fora del sistema ...
Skorupinska, Aleksandra Aldona (Fecha de defensa: 2017-09-28)
La tesi està escrita com un manuscrit de cinc publicacions científiques i presenta una de les primeres evidències de la relació entre les tecnologies de la informació i la comunicació (TIC) i la productivitat en els països ...