Mostrando ítems 11-20 de 26
Cebrià i Costa, Joan Pau (Fecha de defensa: 2017-06-29)
L’oxidació de la histona 3 en la lisina 4 (H3K4ox) per acció de la lysil oxidase-like 2 (LOXL2) genera una nova modificació de la H3 amb una funció desconeguda. En aquesta tesi, hem determinat tant en ...
Trussart, Marie (Fecha de defensa: 2015-10-30)
Des de l’aparició de les tecnologies de seqüenciació d’alt rendiment, els conjunts de dades biològiques han esdevingut cada cop més grans i complexes, la qual cosa els fa pràcticament impossibles ...
Cuscó Pons, Pol (Fecha de defensa: 2017-12-13)
Des de l’aparició de les tecnologies de seqüenciació d’alt rendiment, els conjunts de dades biològiques han esdevingut cada cop més grans i complexes, la qual cosa els fa pràcticament impossibles ...
Dumbović, Gabrijela (Fecha de defensa: 2017-01-12)
DNA hypomethylation of repeats has been found in almost every tumor type studied. Hypomethylation of repetitive elements was shown to increase the likelihood of homologous recombination of these repeated ...
Reina García, Óscar (Fecha de defensa: 2018-04-10)
We developed a computational framework implemented as an R package for generation, visualization and functional and differential analysis of epigenome maps. Methods are provided for integrating and ...
Mocavini, Ivano (Fecha de defensa: 2022-03-31)
Polycomb repressive complex (PRC)1 and 2 are major players in gene regulation, devoted to maintenance of the epigenetic memory of gene silencing. Mouse embryonic stem cells (mESCs) have been extensively ...
Islam, Abul (Fecha de defensa: 2012-06-25)
Recent advances in high throughput technology have opened the door to systematic studies of epigenetic mechanisms. One of the key components in the regulation of the cell cycle and differentiation is ...
Cantacorps Centellas, Lídia (Fecha de defensa: 2019-11-15)
Maternal alcohol binge drinking during pregnancy can be deleterious for the developing foetus, leading to a wide range of long-lasting morphological and neurobehavioural disabilities known as foetal ...
Victor, Pedro Sousa (Fecha de defensa: 2012-02-27)
Muscle aging, in particular, is characterized by the reduction of tissue mass and function, which are particularly prominent in geriatric individuals undergoing sarcopenia. The age-associated muscle ...
Díaz Blanco, Noelia (Fecha de defensa: 2014-10-24)
In many gonochoristic fish, sex is plastic since it can be altered by the influence of environmental factors. In this thesis, using the European sea bass (Dicentrarchus labrax) model, a teleost fish ...